Small-molecule pol u inhibitors provide safe and effective tumor radiosensitization in preclinical models

HIGHLIGHTS

• who: Anil Negi from the Department of Oncology, University of Oxford, Oxford, United Kingdom Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom. Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom. The Francis Crick Institute, London, United Kingdom. have published the paper: Small-Molecule Pol u Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models, in the Journal: (JOURNAL)
• what: The authors evaluate whether targeting Polq with novel smallmolecule is a feasible strategy to improve the efficacy of radiotherapy. The authors show that ART558 and ART899 two novel and specific . . .
  

   

  

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