HIGHLIGHTS
- who: Zaixin Zhang from the (UNIVERSITY) have published the research work: Small molecule targeting FOXM1 DNA binding domain exhibits anti-tumor activity in ovarian cancer, in the Journal: (JOURNAL) of 23/05/2022
- what: The study provides a lead compound of FOXM1 inhibitor which might be as a potential targeted probe for ovarian cancer treatment.
- how: The authors identified XST-20 as a leading compound which could specifically block FOXM1 DNA-binding and inhibits its transcriptional activity. Student`s t-test and one-way analysis of variance (ANOVA) were used to determine significant . . .
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