Small-rna sequencing identifies dynamic microrna deregulation during skeletal muscle lineage progression

HIGHLIGHTS

• who: David Castel from the (UNIVERSITY) have published the Article: Small-RNA sequencing identifies dynamic microRNA deregulation during skeletal muscle lineage progression, in the Journal: (JOURNAL)
• what: The authors provide a genome-wide assessment of the expression of small RNAs during the quiescence/activation transition and differentiation by RNAsequencing. The authors show that the majority of small RNAs present in quiescent, activated and differentiated muscle cells belong to the microRNA class. By comparing expression in distinct cell states, the authors report a massive and dynamic regulation of microRNAs, both in numbers and amplitude, highlighting their . . .
  

   

  

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