Small soluble α-synuclein aggregates are the toxic species in parkinson⠒s disease

HIGHLIGHTS

• who: Derya Emin from the (UNIVERSITY) have published the research work: Small soluble u03b1-synuclein aggregates are the toxic species in Parkinsonu2812s disease, in the Journal: (JOURNAL)
• what: The authors show a reliable non-perturbative method to separate a heterogeneous mixture of protein aggregates by size. The authors focused on the amygdala as the region of interest as recent clinicopathological work has demonstrated that both u03b1-synuclein pathology and neuroinflammation in this region are correlated and associated with the development of PD dementia8. Based on the data , the authors propose that neurons have mechanisms to . . .
  

   

  

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