Smash: a scalable, general marker gene identification framework for single-cell rna-sequencing

HIGHLIGHTS

  • who: M. E. Nelson from the Institute, UK University of have published the article: SMaSH: a scalable, general marker gene identification framework for single-cell RNA-sequencing, in the Journal: (JOURNAL)
  • what: The authors demonstrate the utility of through its substantial performance improvement over several existing methods in the field. The authors evaluate the markers on spatial transcriptomics data demonstrating they identify highly localised compartments of the mouse cortex. The authors propose SMaSH (Scalable Marker (gene) Signal Hunter, Fig 1) for the identification of important genes, from already annotated scRNA-seq data. The authors demonstrate . . .

     

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