HIGHLIGHTS
- who: Zonglei Zhao et al. from the Shandong University, China have published the research: SMC4, a novel tumor prognostic marker and potential tumor therapeutic target, in the Journal: (JOURNAL)
- what: The main reasons for the poor prognoses of pancreatic adenocarcinoma (PA) patients are rapid early-stage progression, chemotherapy resistance, and advanced-stage metastasis. This study provides a new insight into the cofunction of SMC4 and the mechanism by which the TGF b/Smad pathway is hyperactivated in gliomas, indicating that SMC4 is a valuable prognostic factor and a potential therapeutic target in gliomas .
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