Smg6 localizes to the chromatoid body and shapes the male germ cell transcriptome to drive spermatogenesis

HIGHLIGHTS

  • who: from the Institute of Biomedicine, Integrative Physiology and Pharmacology Unit, University of Turku, Turku, Finland, Turku have published the research: SMG6 localizes to the chromatoid body and shapes the male germ cell transcriptome to drive spermatogenesis, in the Journal: (JOURNAL)
  • what: The authors show that SMG6 is essential for male germ cell differentiation in mice. This analysis showed that the percentage of tubules containing at least one apoptotic spermatocyte was >5fold increased (from 13% in control to 70% in Smg6-cKO) and the percentage of tubules with at least one apoptotic round spermatid was . . .

     

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