Smooth-muscle-derived wnt5a augments allergen-induced airway remodelling and th2 type inflammation

HIGHLIGHTS

  • who: Smooth-muscle-derived WNT and colleagues from the DepartmentUniversity of Groningen, Groningen, The Netherlands have published the research: Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation, in the Journal: Scientific Reports Scientific Reports of 13/09/2019
  • what: The authors aimed to characterize the effects of smooth-muscle-derived WNT5A in the lungs, using a doxycycline-inducible TetO-Wnt5a mouse model in combination with SM22-rtTA to drive expression of rtTA under control of the smooth-muscle-specific SM22 promoter. The findings support the idea that the origin of . . .

     

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