Solid lipid-based nanoparticulate system for sustained release and enhanced in-vitro cytotoxic effect of 5-fluorouracil on skin melanoma and squamous cell carcinoma

HIGHLIGHTS

  • who: Ahsan Ali et al. from the Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur have published the article: Solid lipid-based nanoparticulate system for sustained release and enhanced in-vitro cytotoxic effect of 5-fluorouracil on skin Melanoma and squamous cell carcinoma, in the Journal: PLOS ONE of 17/Oct/2022
  • what: In the present study, 5-FU-loaded SLNs were successfully prepared and characterized for physicochemical properties to optimize size distribution for enhanced permeability and retention effects at the cancer site.
  • how: The particle size zeta potential . . .

     

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