Sorafenib and doxorubicin show synergistic effects in human and canine osteosarcoma cell lines

HIGHLIGHTS

• who: Ya-Ting Yang and Vilma Yuzbasiyan-Gurkan from the College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA have published the article: Sorafenib and Doxorubicin Show Synergistic Effects in Human and Canine Osteosarcoma Cell Lines, in the Journal: (JOURNAL)
• what: The authors demonstrated that sorafenib, a multi-kinase inhibitor, acts as an effective drug against both human and canine osteosarcoma cells.
• how: For all TKIs the authors used a high drug dose of 100 µM.
• future: These small cohorts indicate that using sorafenib alone or with other drugs . . .
  

   

  

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