Sorting nexin 17 increases low-density lipoprotein receptor-related protein 4 membrane expression: a novel mechanism of acetylcholine receptor aggregation in myasthenia gravis

HIGHLIGHTS

  • who: Xiaoxiao He from the National University of, University of Turku, Finland have published the article: Sorting nexin 17 increases low-density lipoprotein receptor-related protein 4 membrane expression: A novel mechanism of acetylcholine receptor aggregation in myasthenia gravis, in the Journal: (JOURNAL)
  • what: In the animal model of this study, the authors first explored the effects of SNX17 on AChR aggregation in the AChR-MG mouse model.

SUMMARY

    Myasthenia gravis (MG) is a typical autoimmune disease induced by autoantibodies. In 2013, LRP4 autoantibodies were found to induce LRP4 internalization by . . .

     

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