HIGHLIGHTS
- who: Ryan C. Gimple and collaborators from the Division of Regenerative Medicine, Department of Medicine, University of California, La Jolla, CA, USA have published the paper: Sorting Nexin sustains Platelet-Derived Growth_Factor Receptor signaling in glioblastoma stem_cells via endosomal protein sorting, in the Journal: (JOURNAL)
SUMMARY
As the most prevalent primary intrinsic brain tumor, glioblastomas are highly lethal, with current standard-of-care therapies offering only palliation. The cancer stem_cell hypothesis posits the presence of a stemlike tumor cell state to initiate tumors and recapitulate the cellular diversity of the tumor from which . . .
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