Sox2 haploinsufficiency promotes impaired vision at advanced age

HIGHLIGHTS

  • who: Top from the Cellular Oncology Group, Biodonostia Health Research Institute, San Sebastián, Spain, University of Alcala, Madrid, Spain have published the Article: SOX2 haploinsufficiency promotes impaired vision at advanced age, in the Journal: (JOURNAL)
  • what: The authors explored the effects of Sox2 haploinsufficiency in aged retina. resulting images revealed that the structure of MG and intensity of staining was similar in young mice . The authors show the essential role for Sox2 in the age-associated decline in retinal cell function and visual activity. While these studies demonstrated the need for Sox2 for the . . .

     

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