Sp8 transcriptional regulation of cyclin d1 during mouse early corticogenesis

HIGHLIGHTS

  • who: Ugo Borello from the Max Planck Institute of Molecular Cell Germany Inovarion, Paris, France, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom have published the research: SP8 Transcriptional Regulation of Cyclin D1 During Mouse Early Corticogenesis, in the Journal: (JOURNAL)
  • what: The authors show that SP8 is a critical player in the regulation of Ccnd1 expression during in_vivo mouse corticogenesis. The authors demonstrate that SP8 is able to specifically activate gene_expression from the Ccnd1 exon 5 fragment, containing part of the 3′ UTR, suggesting that the 3′ -end of the Ccnd1 gene . . .

     

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