HIGHLIGHTS
SUMMARY
Interestingly, a central pathophysiological event linking most of these processes is insulin resistance at specific organs, like the liver, the skeletal muscles and the adipose_tissue, but also the blood vessels and the skin and epithelia (Tobin et_al, 2002; Bergouignan et_al, 2011). In this context, a pivotal role in the pathophysiology of the MS and the related increased cardiovascular risk is played by the expanded and dysfunctional visceral adipose_tissue compartment (Neeland et_al, 2019; Ross et_al, 2020). Fasting insulin INSULIN RESISTANCE AND METABOLIC SYNDROME PATHOPHYSIOLOGY AND ASSESSMENT Insulin resistance is the pathophysiological hallmark of the metabolic . . .
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