HIGHLIGHTS
- who: Samuel H. Jungen from the University of Basel, Switzerland have published the research work: Spatial distribution of CD3- and CD8-positive lymphocytes as pretest for POLE wild-type in molecular subgroups of endometrial carcinoma, in the Journal: (JOURNAL)
- what: Our spatial multiplex immunofluorescence approach could decipher a possible diagnostic test for clinical decision making in EC.
- how: For that reason the authors used a spatial digital pathology method to quantitatively examine CD3+ and CD8+ immune infiltrates in comparison to conventional histopathological parameters prognostics and as potential pretest before molecular analysis.
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