Spatial heterogeneity of cancer associated protein expression in immunohistochemically stained images as an improved prognostic biomarker

HIGHLIGHTS

  • who: Henrik Failmezger et al. from the Switzerland Boston University, United States have published the research work: Spatial heterogeneity of cancer associated protein expression in immunohistochemically stained images as an improved prognostic biomarker, in the Journal: (JOURNAL)
  • what: In this technical proof of concept study, the authors present spatial scores to determine the expression heterogeneity of proteins in the tissue which turned out to have enormous potential to serve as future biomarkers in clinical studies. Like the Haralick features, the scores are based on a co-occurrence analysis, however instead of analyzing grey value intensities . . .

     

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