Spatial transcriptomics for profiling the tropism of viral vectors in tissues

HIGHLIGHTS

  • who: Min J. Jang from the (UNIVERSITY) have published the research work: Spatial transcriptomics for profiling the tropism of viral vectors in tissues, in the Journal: (JOURNAL) of 24/03/2022
  • what: USeqFISH also enables profiling of pooled regulatory cargos, as the authors show for a 13-variant pool of microRNA target sites in AAV genomes. Lastly, the authors demonstrate potential applications of USeqFISH for in situ AAV profiling and multimodal single-cell analysis in non-human primates. The authors demonstrate the utility of USeqFISH in the NHP brain with viral tools, illustrating the generalizability . . .

     

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