Spatiotemporal analysis of a glycolytic activity gradient linked to mouse embryo mesoderm development

HIGHLIGHTS

  • who: Vinay Bulusu from the Molecular Biology Laboratory (EMBL), Heidelberg, Germany have published the Article: Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development, in the Journal: (JOURNAL) of February/27,/2017
  • what: Combined the approach identifies a gradient of glycolytic activity across the PSM and the authors provide evidence that these spatiotemporal metabolic changes are intrinsically linked to PSM development and differentiation. While the work was ongoing, two pyruvate biosensors employing a similar strategy using PdhR were reported and successfully used in cell lines, demonstrating the suitability of PdhR as . . .

     

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