Spatiotemporal control of engineered bacteria to express interferon-γ by focused ultrasound for tumor immunotherapy

HIGHLIGHTS

• who: Yuhao Chen from the Centre University of South China, Hengyang, Hunan, China have published the paper: Spatiotemporal control of engineered bacteria to express interferon-γ by focused ultrasound for tumor immunotherapy, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors develop an ultrasound-responsive bacterium (URB) which can spatiotemporally control the gene_expression by focused ultrasound-induced hyperthermia.
• how: Showed that the parameters at 4.93 MPa acoustic pressure 3 s ON and 5 s OFF periodic irradiation could keep the bacterium solution at 45 °C constant temperature (Fig 2d). These results showed . . .
  

   

  

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