Specialized pro-resolving mediators mitigate cancer-related inflammation: role of tumor-associated macrophages and therapeutic opportunities

HIGHLIGHTS

  • who: Margot Lavy from the Institut National de la Santé et de la France University of Milan, Italy have published the research: Specialized Pro-Resolving Mediators Mitigate Cancer-Related Inflammation: Role of Tumor-Associated Macrophages and Therapeutic Opportunities, in the Journal: (JOURNAL)
  • how: This result is in line with lower 5-LOX expression in macrophages from human breast invasive tumors compared with macrophages from normal breast tissues .
  • future: Studies are needed to fully characterize the expression of SPMs and their specific receptors in TAMs to better understand the implications of these pro-resolving . . .

     

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