Species d adenoviruses as oncolytic viral vectors

HIGHLIGHTS

  • who: Brianna L. Bullard et al. from the Nebraska Center for Virology, School of Biological Sciences, University of Nebraska, Lincoln, NE, USA have published the research work: Species D Adenoviruses as Oncolytic Viral Vectors, in the Journal: (JOURNAL)
  • what: The authors investigate the species D Ads cellular transduction, transgene_expression, cytotoxicity, and viral_replication in six different cancer cell lines. Species D Ads have previously been explored for their increased transduction and oncolytic potential against B cell cancers , and here the authors show their potential against solid cancers.
  • future: Biodistribution studies of Ad26 and Ad48 . . .

     

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