Spermine synthase and myc cooperate to maintain colorectal cancer cell survival by repressing bim expression

HIGHLIGHTS

• who: Yubin Guo from the Provincial Key LaboratoryMedical University have published the Article: Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression, in the Journal: Nutritional Sciences,
• what: The authors report that SMS is highly expressed in CRC. The work demonstrates that SMS cooperates with MYC to maintain CRC cell survival via distinct pathways that converge to repress expression of the proapoptotic protein Bim. The study provides several insights into the biology and therapeutic relevance of cooperative SMS and MYC signaling in CRC tumorigenesis.
• how: The authors . . .
  

   

  

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