HIGHLIGHTS
- who: Eric Hajduch from the Centre Recherche des Cordeliers, INSERM, Sorbonne Université, Université, France, Institut The University of Utah, United States have published the Article: Sphingolipid Metabolism and Signaling in Skeletal Muscle: From Physiology to Physiopathology, in the Journal: (JOURNAL)
- what: Given the lack of molecular evidence for a role of intramuscular C16-ceramide production by these two CerS in muscle insulin resistance, other studies focused on C18-ceramide as another potential candidate.
- how: These data indicated that inhibition of SphK2 could be an attractive target to develop treatments to ameliorate insulin resistance . . .
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