HIGHLIGHTS
- who: Luyan Cao from the Universitu00e9University College London, London, UK have published the research: SPIN90 associates with mDia1 and the Arp2/3 complex to regulate cortical actin organization, in the Journal: (JOURNAL)
- what: The authors examine how NPFs regulate nucleator activity in the actin cortex to control its organization assembly kinetics and mechanics. The authors show that IQGAP1 controls the activity of the formin mDia1 WRC regulates Arp2/3 branching activity and mediates an unexpected synergistic action between Arp2/3 and mDia1.
SUMMARY
The authors concentrated on WRC and SPIN90 because . . .

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