Spinal cord pathology is ameliorated by p2x7 antagonism in sod1-mutant mouse model of amyotrophic lateral sclerosis words: p2x7 cellular biology and neurobiology cnr via del fosso di fiorano

HIGHLIGHTS

  • who: Savina Apolloni and collaborators from the Istituto Superiore di Sanità, Rome, Italy have published the Article: Spinal cord pathology is ameliorated by P2X7 antagonism in SOD1-mutant mouse model of amyotrophic lateral sclerosis WORDS: P2X7 Cellular Biology and Neurobiology CNR Via del Fosso di Fiorano, in the Journal: (JOURNAL) of 29/05/2014
  • what: Implications and future directions This study investigates the role of P2X7 in ALS pathogenesis and provides a ‘proof of concept' for the use of P2X7 antagonism as a strategy to ameliorate the neuroinflammatory component of ALS disease. In line with . . .

     

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