Spironolactone alleviates schizophrenia-related reversal learning in tcf4 transgenic mice subjected to social defeat

HIGHLIGHTS

• who: Marius Stephan from the (UNIVERSITY) have published the research work: Spironolactone alleviates schizophrenia-related reversal learning in Tcf4 transgenic mice subjected to social defeat, in the Journal: (JOURNAL) of 19/04/2022
• what: The authors focus on Transcription factor 4 (TCF4), a gene strongly associated not only with the risk of developing schizophrenia but also bipolar disorder and major depressive disorder5,6. The authors report the results of such a combinatorial treatment study with aripiprazole and spironolactone in the 2-hit Tcf4tg x social defeat (Tcf4SD) mouse model. The authors used the previously established . . .
  

   

  

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