HIGHLIGHTS
- who: Janine Dywicki from the (UNIVERSITY) have published the Article: Splenectomy induces biochemical remission and regeneration in experimental murine autoimmune hepatitis, in the Journal: (JOURNAL)
- what: Biochemical remission of emAIH was induced by splenectomy performed during the late stage of disease.
- how: An increase in intrahepatic Tregs correlates with a reduction in ALT Given that the CD4/CD8 ration is decreased in other liver diseases if the disease is worsening the authors analyzed this in the splenectomy emAIH model.
SUMMARY
Similarly, experimental murine AIH (emAIH) can be induced by . . .
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