Split phenomena in amyotrophic lateral sclerosis: current evidences, pathogenetic hypotheses and diagnostic implications

HIGHLIGHTS

  • who: Stefano Zoccolella from the Maggiore della Caritu00e0, Italy Chiba University, Japan have published the research: Split phenomena in amyotrophic lateral sclerosis: Current evidences, pathogenetic hypotheses and diagnostic implications, in the Journal: (JOURNAL)
  • how: A single repetitive nerve stimulation study was conducted in patients with ALS with normal strength hand normal median and ulnar compound muscle action potentials (CMAPs) and in normal subjects.

SUMMARY

    Amyotrophic lateral sclerosis (ALS) involves upper (UMN) and lower motor neuron (LMN), and is fatal on average within 4 years from onset. Several clinical and neurophysiological studies . . .

     

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