Spreading depolarization as a therapeutic target in severe ischemic stroke: physiological and pharmacological strategies

HIGHLIGHTS

  • who: Lily Chau et al. from the Department of Neurology, University of New Mexico, Albuquerque, NM, USA have published the paper: Spreading Depolarization as a Therapeutic Target in Severe Ischemic Stroke: Physiological and Pharmacological Strategies, in the Journal: (JOURNAL)
  • what: The authors demonstrate suppression of recurrent SD in one subject with recurring clusters of SD. For this study, SD and isoelectric SD were grouped together for analysis.
  • how: Plotting the probability of SD in 20-min bins the authors identified blood pressure heart rate ETCO2 and oxygen saturation for analysis .
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