Sqstm-1/p62 potentiates htlv-1 tax-mediated nf-κb activation through its ubiquitin binding function

HIGHLIGHTS

• who: SQSTM- and collaborators from the International Center forlabellisée "Fondation pour la Recherche Médicale", Paris, FranceUniversity Medical have published the Article: SQSTM-1/p62 potentiates HTLV-1 Tax-mediated NF-κB activation through its ubiquitin binding function, in the Journal: Scientific Reports Scientific Reports
• what: The authors show that p62 associates with the Tax/IKK signalosome and that binding of p62 to ubiquitin chains is required for p62 to potentiate Tax activity. And in contrast to the work , these interactions were analyzed in cells and not in_vitro, so that indirect interactions cannot be . . .
  

   

  

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