Src-crkii-c3g-dependent activation of rap1 switches growth hormone-stimulated p44/42 map kinase and jnk/sapk activities*

HIGHLIGHTS

  • who: Ling Ling from the (UNIVERSITY) have published the article: Src-CrkII-C3G-dependent Activation of Rap1 Switches Growth Hormone-stimulated p44/42 MAP Kinase and JNK/SAPK Activities*, in the Journal: (JOURNAL) of March/12,/2003
  • what: The authors demonstrate here that growth hormone (GH) stimulates the activation of Rap1 and Rap2 in NIH-3T3 cells. It has been demonstrated that Rap1 is not upstream of Ras , which is also observed in this study and here the authors report that GH-stimulated Rap activation is not Ras-dependent.
  • how: Numerical data were . . .

     

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