Src family kinases regulate interferon regulatory factor 1 k63 ubiquitination following activation by tlr7/8 vaccine adjuvant in human monocytes and b cells

HIGHLIGHTS

• who: Ugo D’Oro from the State Serum Institute (SSI), Denmark University of Gothenburg have published the paper: Src Family Kinases Regulate Interferon Regulatory Factor 1 K63 Ubiquitination following Activation by TLR7/8 Vaccine Adjuvant in Human Monocytes and B Cells, in the Journal: (JOURNAL)
• what: The authors show that a similar signaling pathway involving TLRs and SFKs controls IRF-1 expression and cytokine production in two other important classes of antigen-presenting cells, namely monocytes and B-lymphocytes, which are key target for vaccine adjuvants. The authors provide evidence that SFKs control the TLR7 . . .
  

   

  

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