Stability of methylphenidate under various ph conditions in the presence or absence of gut microbiota

HIGHLIGHTS

  • who: Julia Aresti-Sanz et al. from the (UNIVERSITY) have published the research: Stability of Methylphenidate under Various pH Conditions in the Presence or Absence of Gut Microbiota, in the Journal: Pharmaceuticals 2021, 733 of /2021/
  • what: The authors focused on the gut bacteria known to inhabit the small intestine, the major site of MPH absorption . Although these studies indicate that MPH can be spontaneously hydrolyzed to RA, none of the studies accounted for the physiological conditions of the small intestine that were considered in the study . Collectively, this study shows that MPH is subjected . . .

     

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