Stable isotopomers of myo-inositol uncover a complex minpp1-dependent inositol phosphate network

HIGHLIGHTS

  • who: Minh Nguyen Trung et al. from the Henning Jessen, Institut fuu0308r Organische Chemie, AlbertLudwigs-Universitu00e4t Freiburg, Freiburg, Germany have published the paper: Stable Isotopomers of myo-Inositol Uncover a Complex MINPP1-Dependent Inositol Phosphate Network, in the Journal: (JOURNAL)
  • what: The current assumption is that MINPP1 dephosphorylates InsP6 to hitherto only sparsely annotated InsP4/3 species .6,7,25-27 However, this activity has only been demonstrated in_vitro and in intact cells overexpressing a cytosolic variant of MINPP1.
  • future: The structures of the intermediates were identified using the information from Figure 2 . . .

     

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