HIGHLIGHTS
- who: Wu Zuo from the Shanghai Institute Academy of Sciences, Shanghai, China, University have published the research: Stage-resolved Hi-C analyses reveal meiotic chromosome organizational features influencing homolog alignment, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors employed mouse spermatogenesis as a model system to investigate mammalian meiotic chromosome organization and its functional significance, particularly in the regulation of homolog interactions. Using this approach, the authors show that the size of meiotic chromatin loops increased from ~500 kb in leptotene to ~700 kb in zygotene, eventually reaching ~1.4 Mb in pachytene . . .
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