Startrek: in silico estimation of rna half‑lives from genome‑wide time‑course experiments without transcriptional inhibition

HIGHLIGHTS

  • who: Federica Conte from the Department of Computer, University of Rome, Rome, Italy have published the research: StaRTrEK: in silico estimation of RNA halfu2011lives from genomeu2011wide timeu2011course experiments without transcriptional inhibition, in the Journal: (JOURNAL)
  • what: To show the performance of the proposed algorithm when dealing with a small number of samples, the authors focused on genome-wide yeast transcript half-lives and expression time-course data obtained in response to oxidative and DNA damage stress both collected by Shalem and co-workers , consisting of six time points for each gene and condition.
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