Stat3-mediated osteogenesis and osteoclastogenesis in osteoporosis

HIGHLIGHTS

  • who: Xiaoli Hou from the (UNIVERSITY) have published the Article: STAT3-mediated osteogenesis and osteoclastogenesis in osteoporosis, in the Journal: (JOURNAL)
  • what: To the abovementioned miRNAs that directly or indirectly target STAT3, other studies focusing on cartilage or nonskeletal tissue indicate a more complicated mechanism and network that STAT3 mediates during the development of a series of diseases.
  • how: These results showed that the accumulation of HA in bone marrow cells may affect RANKL-mediated osteoclast-supporting activity by regulating the VDR and STAT3 signalling pathways . These results showed that haematopoietic cell-derived . . .

     

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