Stat3 stabilizes ikk protein through direct interaction in transformed and cancerous human breast epithelial cells

HIGHLIGHTS

• who: Young-Il Hahn and collaborators from the Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University have published the research: STAT3 Stabilizes IKK Protein through Direct Interaction in Transformed and Cancerous Human Breast Epithelial Cells, in the Journal: (JOURNAL)
• what: STAT3 stabilizes and up-regulates IKKu03b1 expression, responsible for the non-canonical NF-u03baB activation, in H-Ras MCF-10A cells, exacerbating tumorigenesis (Figure 6).
• future: Investigation is required to fully elucidate the underlying mechanism. Studies will . . .
  

   

  

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