Stat6 inhibits ferroptosis and alleviates acute lung injury via regulating p53/slc7a11 pathway

HIGHLIGHTS

• who: Youjing Yang from the C BL/6, STAT6flox/flox and SftpcCre mice were purchased from Cyagen Biosciences (Guangzhou, China)STAT6flox/flox mice were crossed with SftpcCre mice to generate lung epithelium-specific , knockout (STAT6cKO) mice. All mice received standard laboratory diet and maintained in , h light/dark cycle, climate-controlled and pathogen-free rooms. Mice handling in this study followed the Guide for the Care and Use of Laboratory Animals and the study protocols were approved by Soochow University Institutional Animal Care and Use Committee. Six to eight weeks old gender-matched wildtype and knockout mice . . .
  

   

  

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