State-of-the-art estimation of protein model accuracy using alphafold

HIGHLIGHTS

  • who: Editors`, Suggestion and James P., Roney from the Harvard University, Cambridge, Massachusetts, USA have published the research: State-of-the-Art Estimation of Protein Model Accuracy Using AlphaFold, in the Journal: (JOURNAL) of 28/Nov/2022
  • what: The authors provide evidence that AlphaFold has learned such an energy function and uses coevolution data to solve the global search problem of finding a low-energy conformation. The authors demonstrate that AlphaFold`slearned energy function can be used to rank the quality of candidate protein structures with state-of-the-art accuracy without using any coevolution . . .

     

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