Statistical evidence for the presence of trajectory in single-cell data

HIGHLIGHTS

  • who: Lovemore Tenha from the Department of Computer University, Las Cruces, USA have published the paper: Statistical evidence for the presence of trajectory in single-cell data, in the Journal: (JOURNAL)
  • what: Although the approach is also MST based, the authors design different statistics to emphasize the existence of a global trajectory structure. The authors demonstrate how the three test statistics report existence of trajectory in singlecell RNA-seq datasets that are simulated or real observations.
  • future: The future work will focus on optimizing the computation process as well as identifying analytical null . . .

     

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