Stellate cells aid growth-permissive metabolic reprogramming and promote gemcitabine chemoresistance in pancreatic cancer

HIGHLIGHTS

  • who: Manoj Amrutkar and Ivar P. Gladhaug from the Department of Pharmacology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway have published the research work: Stellate Cells Aid Growth-Permissive Metabolic Reprogramming and Promote Gemcitabine Chemoresistance in Pancreatic Cancer, in the Journal: Cancers 2021, 13, 601. of /2021/
  • what: Unlike many other solid tumors, pancreatic tumors are extremely chemoresistant and highly metabolically active.
  • future: Various attempts to alter or target PSCs and their secretions have largely been unsuccessful underscoring the importance of future investigations into the roles of PSCs in attempts to . . .

     

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