Stemness analysis uncovers that the peroxisome proliferator-activated receptor signaling pathway can mediate fatty acid homeostasis in sorafenib-resistant hepatocellular carcinoma cells

HIGHLIGHTS

  • who: Tingze Feng from the National Cancer Institute (NIH), United States Yogi Vemana University, India have published the paper: Stemness Analysis Uncovers That The Peroxisome Proliferator-Activated Receptor Signaling Pathway Can Mediate Fatty Acid Homeostasis In Sorafenib-Resistant Hepatocellular Carcinoma Cells, in the Journal: (JOURNAL)
  • what: Based on the results of the study , the authors thought that, in addition to commonly reported pathways, PPAR-related activities associated with fatty_acid metabolism might also affect the response to sorafenib treatment.
  • how: In total the authors obtained seven HCC cohorts involving a total of 991 samples . . .

     

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