Stepwise differentiation of functional pancreatic β cells from human pluripotent stem cells

HIGHLIGHTS

  • who: Wenwen Jin from the (UNIVERSITY) have published the research work: Stepwise differentiation of functional pancreatic β cells from human pluripotent stem cells, in the Journal: (JOURNAL)
  • what: To date, significant advances have been made in stepwise pancreatic differentiation.
  • how: The results showed that the patients developed a mixed meal-stimulated C-peptide secretion after transplantation.

SUMMARY

    Type 1 diabetes is caused by a dysregulated autoimmune reaction towards pancreatic β cells, while type 2 diabetic patients suffer an insulin action deficiency caused by pancreatic β cell dysfunction and peripheral insulin resistance (Katsarou . . .

     

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