Sterol regulatory element binding protein- dependent regulation of lipid synthesis supports cell survival and tumor growth

HIGHLIGHTS

  • who: Equal contributors and collaborators from the Institute, Lincoln's Inn Fields, London WC A LY, UK have published the Article: Sterol regulatory element binding protein- dependent regulation of lipid synthesis supports cell survival and tumor growth, in the Journal: (JOURNAL)
  • what: This study shows that SREBP is essential for cancer cell survival and has a role in the regulation of lipid metabolism, protein homeostasis, stress response and cellular redox balance.
  • how: As the three main transcription factors associated with the ER-stress are ATF4 ATF6 and XBP-1 the authors compared the . . .

     

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