HIGHLIGHTS
- who: Lingfang Zeng from the (UNIVERSITY) have published the Article: Sterol-responsive Element-binding Protein (SREBP) 2 Down-regulates ATP-binding Cassette Transporter A1 in Vascular Endothelial Cells, in the Journal: (JOURNAL) of July/12,/2004
- what: The authors reported that the binding of SREBP2(N) to E-box motif within the hABCA1 promoter is responsible for the repressive effect of serum deprivation and oscillatory flow on the expression of ABCA1 in ECs.
- how: The results showed that sterol depletion activated SREBP2 and increased its target low density lipoprotein receptor mRNA with a . . .
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