HIGHLIGHTS
- who: Dhruti Patwardhan from the PROTECT, INSERM, Université Paris Diderot, Sorbonne Paris Cité, Paris, France have published the research: STIL balancing primary microcephaly and cancer, in the Journal: (JOURNAL)
- how: This review describes the recent advances on STIL functions in the control of centriole duplication and mitotic spindle integrity and discusses how pathological perturbations of its finely tuned expression result in chromosomal instability in both embryonic and postnatal situations highlighting the concept that common key factors are involved in developmental steps and tissue homeostasis.
SUMMARY
The developing brain appears particularly sensitive . . .
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