Sting agonist delivery by tumour-penetrating peg-lipid nanodiscs primes robust anticancer immunity

HIGHLIGHTS

• who: Eric L. Dane from the Koch Institute of Technology, Cambridge, MA, USAHarvard University have published the research work: STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity, in the Journal: (JOURNAL) of 23/05/2022
• what: The authors demonstrate that LNDs carrying an effective immunotherapy following a single intravenous systemic administration in multiple tumour models. Through in vitro in vivo and in silico experiments the authors show that the unique properties of carriers enable superior tumour penetration and tumour cell uptake resulting in improved antitumour T-cell priming and long . . .
  

   

  

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