Sting-pathway modulation to enhance the immunogenicity of adenoviral-vectored vaccines

HIGHLIGHTS

• who: Eriko Padron-Regalado from the The Jenner InstituteUniversity of Oxford, Oxford, UK have published the paper: STING-pathway modulation to enhance the immunogenicity of adenoviral-vectored vaccines, in the Journal: Scientific Reports Scientific Reports
• how: The results indicated that 2u20323u2032-cGAMP induced lower Pb9 and u00adeGFP200-208-specific immune_responses compared to its linear analogue (two-way ANOVA main effect analysis **p=0.0095 and *p=0.0402 respectively) (Fig 2c-f). The final data is presented as spot-forming cells (SFC) per million splenocytes after subtracting the background (number of IFN-u03b3 SFC in . . .
  

   

  

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